Original Publications

  • Annett Erkes, Stefanie Mücke, Maik Reschke, Jens Boch, Jan Grau (2019) PrediTALE: A novel model learned from quantitative data allows for new perspectives on TALE targetingbioRxiv 522458
    DOI: https://doi.org/10.1101/522458
  • Stefanie Mücke, Maik Reschke, Annett Erkes, Claudia-Alice Schwietzer, Sebastian Becker, Jana Streubel, Richard D. Morgan, Geoffrey G. Wilson, Jan Grau and Jens Boch (2019) Transcriptional Reprogramming of Rice Cells by Xanthomonas oryzae TALEsFront. Plant Sci., 25 February 2019
    DOI: https://doi.org/10.3389/fpls.2019.00162
  • Ordon, J., Gantner, J., Kemna, J., Schwalgun, L., Reschke, M., Streubel, J., Boch, J., and Stuttmann, J. (2017) Generation of chromosomal deletions in dicotyledonous plants employing a user-friendly genome editing toolkitPlant J. 89, 155-168 Weitere Informationen
    ISBN: 10.1111/tpj.13319
  • Streubel, J., Baum, H., Grau, J., Stuttman, J., and Boch, J. (2017) Dissection of TALE-dependent gene activation reveals that they induce transcription cooperatively and in both orientations. PLoS ONE 12, e0173580
    DOI: http://dx.doi.org/10.1371/journal.pone.0173580
  • Volohonsky, G., Hopp, A.-K., Saenger, M., Soichot, J., Scholze, H., Boch, J., Blandin, S.A., Marois, E. (2017) Transgenic expression of the anti-parasitic factor TEP1 in the malaria mosquito Anopheles gambiaePLoS Pathog. 13, e1006113 Weitere Informationen
    DOI: 10.1371/journal.ppat.1006113
  • Becker, S., Boch, J. (2016) Single-molecule biophysics: TALEs spin along, but not aroundNat. Chem. Biol. 12, 766-768 Weitere Informationen
  • Grau, J., Reschke, M., Erkes, A., Streubel, J., Morgan, R.D., Wilson, G.G., Koebnik, R. and Boch, J. (2016) AnnoTALE: bioinformatics tools for identification, annotation, and nomenclature of TALEs from Xanthomonas genomic sequencesSci. Rep. 6, 21077 Weitere Informationen
    DOI: 10.1038/srep21077
  • Hutin, M., Césari, S., Chalvon, V., Michel, C., Tran, T.T., Boch, J., Koebnik, R., Szurek, B., and Kroj, T. (2016) Ectopic activation of the rice NLR heteropair RGA4/RGA5 confers resistance to bacterial blight and bacterial leaf streak diseasesPlant J. 88, 43-55 Weitere Informationen
  • Geissler, R., Hauber, I., Funk, N., Richter, A., Behrens, M., Renner, I., Chemnitz, J., Hofmann-Sieber, H., Baum, H., van Lunzen, J., Boch, J., Hauber, J., and Behrens, S.E. (2015) Patient-adapted, specific activation of HIV-1 by customized TAL effectors (TALEs), a proof of principle study.Virology 488:248-254. Weitere Informationen
  • Boch, J., Bonas, U., and Lahaye, T. (2014) TAL effectors - pathogen strategies and plant resistance engineeringNew Phytol. 204, 823-832 Weitere Informationen
    DOI: 10.1111/nph.13015
  • Richter, A., Streubel, J., Blücher, C., Szurek, B., Reschke, M., Grau, J., and Boch, J. (2014) A TAL effector repeat architecture for frameshift binding.Nat. Commun. 5, 3447. Weitere Informationen
  • Arrieta-Ortiz, M.L., Rodriguez-R., L.M., Perez-Quintero, A.L., Poulin, L., Diaz, A.C., Rojas, N.A., Trujillo, C., Restrepo Benavides, M., Bart, R., Boch, J., Boureau, T., Darrasse, A., David, P., Duge de Bernonville, T., Fontanilla, P., Gagnevin, L., Guerin, F., Jacques, M.-A., Lauber, E., Lefeuvre, P., Medina, C., Medina, E., Montenegro, N., Munoz Bodnar, A., Noel L.D., Ortiz Quinones, J.F., Osorio, D., Pardo, C., Patil, P.B., Poussier, S., Pruvost, O., Robene-Soustrade, I., Ryan, R.P., Tabima, J., Urrego Morales, O.G., Verniere, C., Carrere, S., Verdier, V., Szurek, B., Restrepo, S., Lopez, C., Koebnik, R., Bernal, A. (2013) Genomic survey of pathogenicity determinants and VNTR markers in the cassava bacterial pathogen Xanthomonas axonopodis pv. manihotis strain CIO151 PLoS ONE 8, e79704 Weitere Informationen
    DOI: 10.1371/journal.pone.0079704
  • Grau, J., Boch, J., and Posch, S. (2013) TALENoffer: genome-wide TALEN off-target prediction. Bioinformatics 29, 2931-2932. Weitere Informationen
  • Grau, J., Wolf, A., Reschke, M., Bonas, U., Posch, S., and Boch, J. (2013) Computational predictions provide insights into the biology of TAL effector target sites. PLoS Comp. Biol. 9, e1002962. Weitere Informationen
  • Richter, A. and Boch, J. (2013) Designer TALEs team up for highly efficient gene induction. Nat. Methods 10, 207-208. Weitere Informationen
  • Streubel, J., Pesce, C., Hutin, M., Koebnik, R., Boch, J., and Szurek, B. (2013) Five phylogenetically close rice SWEET genes confer TAL effector-mediated susceptibility to Xanthomonas oryzae pv. oryzae. New Phytol. 200, 808-819. Weitere Informationen
  • Streubel, J., Richter, A., Reschke, M., and Boch, J. (2013) TALEs - Proteine mit programmierbarer DNA-Bindespezifität. BIOspektrum 19, 370-372. Weitere Informationen
  • Nau-Wagner, G., Opper, D., Rolbetzki, A., Boch, J., Kempf, B., Hoffmann, T., and Bremer, E. (2012) Genetic control of osmoadaptive glycine betaine synthesis in Bacillus subtilis through the choline-sensing and glycine betaine-responsive GbsR repressor. J. Bacteriol. 194, 2703-2714. Weitere Informationen
  • Streubel, J., Blücher, C., Landgraf, A., and Boch, J. (2012) TAL effector RVD specificities and efficiencies. Nat. Biotechnol. 30, 593-595. Weitere Informationen
  • Boch, J. (2011) TALEs of genome targeting.Nat. Biotechnol. 29, 135-136. Weitere Informationen
  • Geißler, R., Scholze, H., Hahn, S., Streubel, J., Bonas, U., Behrens, S.-E., and Boch, J. (2011) Transcriptional activators of human genes with programmable DNA-specificity. PLoS ONE 6, e19509. Weitere Informationen
  • Scholze, H. and Boch, J. (2011) TAL effectors are remote controls for gene activation.Curr. Opin. Microbiol. 14, 47-53. Weitere Informationen
  • Yu, Y., Streubel, J., Balzergue, S., Champion, A., Boch, J., Koebnik, R., Feng, J.-X., Verdier, V., and Szurek, B. (2011) Colonization of rice leaf blades by an African strain of Xanthomonas oryzae pv. oryzae depends on a new TAL effector which induces the rice nodulin-3 Os11N3 gene. Mol. Plant-Microbe Interact. 24, 1102-1113. Weitere Informationen
  • Boch, J. and Bonas, U. (2010) Xanthomonas AvrBs3 family-type III effectors: discovery and function. Annu. Rev. Phytopathol. 48, 419-436. Weitere Informationen
  • Morbitzer, R., Römer, P., Boch, J., and Lahaye, T. (2010) Regulation of selected genome loci using de novo-engineered transcription activator-like effector (TALE)-type transcription factors.Proc. Natl. Acad. Sci. USA 107, 21617-21622. Weitere Informationen
  • Römer, P., Recht, S., Strauß, T., Elsaesser, J., Schornack, S., Boch, J., Wang, S., and Lahaye, T. (2010) Promoter elements of rice susceptibility genes are bound and activated by specific TAL effectors from the bacterial blight pathogen, Xanthomonas oryzae pv. oryzae. New Phytol. 187, 1048-1057. Weitere Informationen
  • Scholze, H. and Boch, J. (2010) TAL effector-DNA specificity. Virulence 1, 428-432. Weitere Informationen
  • Boch, J., Scholze, H., Schornack S., Landgraf, A., Hahn, S., Kay, S., Lahaye, T., Nickstadt, A., and Bonas, U. (2009) Breaking the code of DNA binding specificity of TAL-type III effectors. Science 326, 1509-1512; published online 29 October 2009 (10.1126/science.1178811). Weitere Informationen
  • de Torres, M., Mansfield, J., Grabov, N., Brown, I.R., Ammouneh, H., Tsiamis, G., Forsyth, A., Robatzek, S., Grant, M., and Boch, J. (2006) Pseudomonas syringae effector AvrPtoB suppresses basal defence in Arabidopsis. Plant J. 47, 368-382. Weitere Informationen
  • Krause, A., Ramakumar, A., Bartels, D., Battistoni, F., Bekel, T., Boch, J., Böhm, M., Friedrich, F., Hurek, T., Krause, L., Linke, B., McHardy, A.C., Sarkar, A., Schneiker, S., Syed, A.A., Thauer, R., Vorhölter, F.J., Weidner, S., Pühler, A., Reinhold-Hurek, B., Kaiser, O., and Goesmann, A. (2006) Complete genome of the mutualistic, N2-fixing grass endophyte Azoarcus sp. strain BH72.Nat. Biotechnol. 24, 1385-1391. Weitere Informationen
  • Landgraf, A., Weingart, H., Tsiamis, H., and Boch, J. (2006) Different versions of Pseudomonas syringae pv. tomato DC3000 exist due to the activity of an effector transposon. Mol. Plant Pathol. 7, 355-364. Weitere Informationen
  • Kabisch, U., Landgraf, A., Krause, J., Bonas, U., and Boch, J. (2005) Type III secretion chaperones ShcS1 and ShcO1 from Pseudomonas syringae pv. tomato DC3000 bind more than one effector.Microbiology 151, 269-280.
  • Kay, S., Boch, J., and Bonas, U. (2005) Characterization of AvrBs3-like effectors from a Brassaceae pathogen reveals virulence and avirulence activities and a protein with a novel repeat architecture.Mol. Plant-Microbe Interact. 18, 838-848. Weitere Informationen
  • Thieme, F., Koebnik, R., Bekel, T., Berger, C., Boch, J., Büttner, D., Caldana, C., Gaigalat, L., Goesmann, A., Kay, S., Kirchner, O., Lanz, C., Linke, B., McHardy, A. C., Meyer, F., Mittenhuber, G., Nies, D. H., Niesbach-Klösgen, U., Patschkowski, T., Rückert, C., Rupp, O., Schneiker, S., Schuster, S. C., Vorhölter, F., Weber, E., Pühler, A., Bonas, U., Bartels, D., and Kaiser, O. (2005) Insights into genome plasticity and pathogenicity of the plant pathogenic bacterium Xanthomonas campestris pv. vesicatoria revealed by the complete genome sequence.J. Bacteriol. 187, 7254-7266. Weitere Informationen
  • Boch, J., Joardar, V., Gao, L., Robertson, T.L., Lim, M., and Kunkel, B.N. (2002) Identification of Pseudomonas syringae pv. tomato genes induced during infection of Arabidopsis thaliana. Mol. Microbiol. 44, 73-88. Weitere Informationen
  • Jackson, R.W., Mansfield, J.W., Ammouneh, H., Dutton, L.C., Wharton, B., Ortiz-Barredo, A., Arnold, D.L., Tsiamis, G., Sesma, A., Butcher, D., Boch, J., Kim, Y.J., Martin, G.B., Tegli, S., Murillo, J., and Vivian, A. (2002) Location and activity of members of a family of virPphA homologues in pathovars of Pseudomonas syringae and P. savastanoi. Mol. Plant Pathol. 3, 205-216. Weitere Informationen
  • Chen, Z., Kloek, A.P., Boch, J., Katagiri, F., and Kunkel, B.N. (2000) The Pseudomonas syringae avrRpt2 gene product promotes pathogen virulence from inside plant cells. Mol. Plant-Microbe Interact. 13, 1312-1321. Weitere Informationen
  • Nennstiel, D., Boch, J., and Bonas, U. (2000) Bakterielle Phytopathogenese - Xanthomonas als Modellorganismus. Biospektrum 6, 23-26.
  • Ullrich, M.S., Schergaut, M., Boch, J., and Ullrich, B. (2000) Temperature-responsive genetic loci in the plant pathogen Pseudomonas syringae pv. glycinea.Microbiology 146, 2457-2468. Weitere Informationen
  • Kappes, R.M., Kempf, B., Kneip, S., Boch, J., Gade, J., Meier-Wagner, J., and Bremer, E. (1999) Two evolutionarily closely related ABC transporters mediate the uptake of choline for synthesis of the osmoprotectant glycine betaine in Bacillus subtilis.Mol. Microbiol. 32, 203-216. Weitere Informationen
  • Nau-Wagner, G., Boch, J., Le Good, J.A., and Bremer, E. (1999) High-affinity transport of choline-O-sulfate and its use as a compatible solute in Bacillus subtilis. Appl. Environ. Microbiol. 65, 560-568. Weitere Informationen
  • Boch, J., Verbsky, M.L., Robertson, T.L., Larkin, J.C., and Kunkel, B.N. (1998) Analysis of resistance gene-mediated defense responses in Arabidopsis thaliana plants carrying a mutation in CPR5.Mol. Plant-Microbe Interact. 11, 1196-1206. Weitere Informationen
  • Hettwer, U., Jaeckel, F.R., Boch, J., Meyer, M., Rudolph, K., and Ullrich, M.S. (1998) Cloning, nucleotide sequence, and expression in Escherichia coli of levansucrase genes from the plant pathogens Pseudomonas syringae pv. glycinea and P. syringae pv. phaseolicola. Appl. Environ. Microbiol. 64, 3180-3187. Weitere Informationen
  • Boch, J., Nau-Wagner, G., Kneip, S., and Bremer, E. (1997) Glycine betaine aldehyde dehydrogenase from Bacillus subtilis: characterization of an enzyme required for the synthesis of the osmoprotectant glycine betaine.Arch. Microbiol. 168, 282-289. Weitere Informationen
  • Boch, J., Kempf, B., Schmid, R., and Bremer, E. (1996) Synthesis of the osmoprotectant glycine betaine in Bacillus subtilis: characterization of the gbsAB genes.J. Bacteriol.. 178, 5121-5129. Weitere Informationen
  • Boch, J., Kempf, B., and Bremer, E. (1994) Osmoregulation in Bacillus subtilis: synthesis of the osmoprotectant glycine betaine from exogenously provided choline. J. Bacteriol. 176, 5364-5371. Weitere Informationen

Book Articles

  • Richter, A., Streubel, J., Boch, J. (2016) TAL effector DNA-binding principles and specificitiy.TALENs - Methods and Protocols, R. Kühn, W. Wurst, B. Wefers, eds., (New York: Springer), Methods in Molecular Biology, Vol. 1338, pp. 9-25. Weitere Informationen
  • Richter, A., Streubel, J., and Boch, J. (2015) TAL effector DNA-binding principles and specificity.In R. Kühn, W. Wurst, B. Wefers (Eds.), TALENs: Methods and Protocols. Methods in Molecuar Biology. Vol. 1338, New York: Springer. pp. 9-25 Weitere Informationen
  • Boch, J. (2009) The art of manipulation: bacterial type III effectors and their plant targets. In Plant pathogenic bacteria: genomics and molecular biology, R.W. Jackson, ed (Norfolk, UK: Caister Academic Press), pp. 241-271. Weitere Informationen
  • Boch, J., and Bonas, U. (2001) Gram-negative plant pathogenic bacteria.In Emerging Bacterial Pathogens, I. Mühldorfer and K.P. Schäfer, eds (Basel: Karger), pp. 186-196. Weitere Informationen